A global human health risk assessment for Decamethylcyclopentasiloxane (D5)
نویسندگان
چکیده
منابع مشابه
Characterization of ecological risks from environmental releases of decamethylcyclopentasiloxane (D5).
Decamethylcyclopentasiloxane (D5) is used in personal care products and industrial applications. The authors summarize the risks to the environment from D5 based on multiple lines of evidence and conclude that it presents negligible risk. Laboratory and field studies show that D5 is not toxic to aquatic organisms or benthic invertebrates up to its solubility limit in water or porewater or its s...
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متن کاملToxicology and humoral immunity assessment of decamethylcyclopentasiloxane (D5) following a 1-month whole body inhalation exposure in Fischer 344 rats.
D5 is a low-molecular-weight cyclic siloxane used for industrial and consumer product applications. The objective of the present study was to assess potential toxic and immunomodulatory consequences of inhalation exposure to D5. Male and female Fischer 344 rats (25/group) were exposed by whole body inhalation to 0, 10, 25, 75, or 160 ppm D5 6 h/day, 7 days/week for 28 days. Clinical signs, body...
متن کاملComments on the safety assessment of decamethylcyclopentasiloxane (D5) published in regulatory toxicology and pharmacology, 2017, 83:117-118.
This letter is in response to the summary of the safety assessment of the Scientific Committee on Consumer Safety (SCCS) on decamethylcyclopentasiloxane (D5) in cosmetic products published (SCCS & Rousselle, 2017) and the opinion (SCCS, 2017). We have been asked by the Silicones Environmental, Health and Safety Center of the American Chemistry Council to provide comments given that SCCS (2017) ...
متن کاملExposure Assessment to Environmental Pollutants in Human Health Risk Assessment Studies; Overview on New Approaches
Background & objectives: Because of human exposure to various environmental risk factors during the lifetime, the actual exposure estimation has been considered as one of the most important challenges for researchers and decision makers. Considering the contribution of environmental risk factors in the burden of diseases, this study aimed to provide new approaches in exposure assessment filed b...
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ژورنال
عنوان ژورنال: Regulatory Toxicology and Pharmacology
سال: 2016
ISSN: 0273-2300
DOI: 10.1016/j.yrtph.2015.10.023